100% Natural Kava Kava Extract Kava Lactones 30% by HPLC

Abstract:Kava Kava ExtractBotanical Source: Piper methyticum L.Part Used: RootCAS No.: 9000-38-8  Molecular Formula: C21H26N2O3Molecular Weight: 274.269Specification: Kavalactones 30%  70% by HPLCFunctions:Kava\'s active principal ingredients are the kavalactones, of which at least 15 have been identified and

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Abstract:
Kava Kava Extract
Botanical Source: Piper methyticum L.
Part Used: Root
CAS No.: 9000-38-8  
Molecular Formula: C21H26N2O3
Molecular Weight: 274.269
Specification: Kavalactones 30%  70% by HPLC

Functions:
Kava's active principal ingredients are the kavalactones, of which at least 15 have been identified and are all considered psychoactive. Only six of them produce noticeable effects, and their concentrations in kava plants vary. Different ratios can produce different effects. Desmethoxyyangonin, one of the six major kavalactones, is a reversible MAO-B inhibitor (Ki 280 nM) and is able to increase dopamine levels in the nucleus accumbens. This finding might correspond to the slightly euphoric action of kava.
Kava is used to calm anxiety, stress, and restlessness, and treat sleep problems (insomnia). It is also used for attention deficit-hyperactivity disorder (ADHD), epilepsy, psychosis, depression, migraines and other headaches, chronic fatigue syndrome (CFS), common cold and other respiratory tract infections, tuberculosis, muscle pain, and cancer prevention.
Some people use kava for urinary tract infections (UTIs), pain and swelling of the uterus, venereal disease, menstrual discomfort, and to arouse sexual desire.
 
Analysis ItemsSpecificationsResults Methods used
IdentificationPositiveConformsTLC
AppearanceFine Yellow PowderConformsVisual test
Odor & TasteCharacteristicConformsOrganoleptic test
Bulk Density45-55g/100mlConformsASTM D1895B
Particle Size99% through 80 meshConformsAOAC 973.03
Solubility100% soluble in waterConformsVisual
        
AssayNLT 70% Kavalactones70.13%HPLC
Loss on DryingNMT 5.0%3.43%USP
Ash ContentNMT 5.0%4.02%2g /525ºC /3hrs
Extract SolventsWater & EthanolConforms/
Solvent ResiduesNMT 0.05%ConformsGC
        
Heavy MetalsNMT 10ppmConformsAtomic Absorption
Arsenic (As)NMT 2ppmConformsAtomic Absorption
Lead (Pb)NMT 2ppmConformsAtomic Absorption
Cadmium (Cd)NMT 1ppmConformsAtomic Absorption
Mercury(Hg)NMT 0.2ppmConformsAtomic Absorption
        
666NMT 0.1ppmConformsGC
DDTNMT 0.5ppmConformsGC
AcephateNMT 0.2ppmConformsGC
    
Parathion-ethylNMT 0.2ppmConformsGC
PCNBNMT 0.1ppmConformsGC
    

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